基于棉花纤维品质性状的全基因组选择方法的评价与优化
首发时间:2023-05-10
摘要:全基因组选择在棉花中的应用尚处于初级阶段,诸多影响棉花全基因组选择的因素需要进一步深入探究。在前人研究的基础上,本研究利用12种参数和非参数预测模型对1224份陆地棉的4个纤维品质性状进行了全基因组预测,探究了标记密度、群体规模和群体结构对预测准确性的影响。结果表明。12种参数和非参数方法中,LASSO方法最稳定,且参数方法预测效果整体高于非参数方法。4个纤维品质性状的预测准确性均随标记数目和训练群体大小增加而逐渐提高,直至达到平台期。不同亚群间和亚群内的预测发现,训练群体和育种群体的亲缘关系越近,其预测准确性越高。研究结果将进一步加快棉花全基因组选择的研究进程,为棉花实际育种工作提供一定的理论依据及参考建议。
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Evaluation and optimization of a genome-wide selection method based on cotton fiber quality traits
Abstract:The application of genomic selection in cotton is still in the development stage and many factors affecting genomic selection in cotton need to be further study. Based on previous studies, the whole-genome prediction of 4 fiber quality traits in 1224 upland cotton samples was conducted by using 12 parameter and non-parametric prediction models, and the effects of marker density, population size and population structure on the prediction accuracy were investigated. The results show that the LASSO method is the most robust among the 12 methods, and the prediction effect of the parametric method is higher than that of the non-parametric method. The prediction accuracy of the four fiber quality traits increased gradually with the increase of the number of markers and the size of the training population until reaching the plateau. It was found that the closer the genetic relationship between the training population and the prediction population, the higher the prediction accuracy. The results of this study will further accelerate the research process of the whole genome selection of cotton and provide some theoretical basis and reference for the practical breeding of cotton.
Keywords: Genome selection Fiber quality traits Accuracy of prediction
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